In 2000, landed Gale Harold’s breakthrough role as the unapologetic homosexual Brian Kinney, on Showtime’s popular gay drama Queer as Folk. The show elicited a great deal of public controversity but ran for five successful seasons, ending in 2005. He guest-starred in the HBO series Deadwood and also on the CBS series The Unit. In 2006 he went back to the stage in Tenessee Williams’ play Suddenly Last Summer as Dr. Cukrowicz (“Dr. Sugar”). In 2006 he played te lead role in the romantic comedy Falling for Grace. Harold joined the cast of Desperate Housewives as Susan Mayer’s love interest but had a motorcycle accident and left the show. He made a return on May 3, 2009. It is still not known if he will return for the fall 2009 season.
Mark Ruffalo began his career with minor roles in films such as The Dentist (1996), Safe Men (1998) and Ride with the Devil (1999). These led him to some plays including This is Our Youth (1998), which in turn led to Ruffalo’s role as Laura Linney’s troubled, aimless drifter brother Terry in Longeran’s acclaimed, Academy Award-nominated 2000 film You Can Count on Me.
He has landed significant roles in films including, XX/XY (2002), Isabel Coixet’s My Life Without Me alongside Sarah Polley (2003), and We Don’t Live Here Anymore (2004). In 2004 he appeared opposite Tom Cruise in the crime-thriller Collateral (2004). After this he appeared in Just Like Heaven (2005) and Rumor Has It (2005). In 2006, Ruffalo starred in Clifford Odets’s Awake and Sing! at the Belasco Theater in New York, for which he was nominated for a Tony Award for Best Featured Actor in a Play. In 2007, he appeared in Zodiac and Reservation Road.
Jason Segel became known when he landed the role on the TV series Freaks and Geeks. He had some recurring roles on CSI: Crime Scene Investigation as Neil Jansen and on Undeclared as Eric. He then landed a role as Marshall on the CBS sitcom How I Met Your Mother. Some of the films that Segel has appeared in are, Slackers, SLC Punk!, The Good Humor Man, Dead Man on Campus and Knocked Up. Segel starred in the lead role of 2008′s Forgetting Sarah Marshall. His newest film is I Love You, Man (2009).